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Theory of Probability and Mathematical Statistics



Goodness-of-fit test in Cox proportional hazards model with measurement errors

A. G. Kukush, O. O. Chernova

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Abstract: Cox proportional hazards model with measurement errors is studied, in which baseline hazard rate λ(·) belongs to a parameter set consisting of nonnegative Lipschitz functions, with fixed constant, and regression parameter β belongs to a compact parameter set. Censored lifetime and regressors with additive errors are observed. We construct a goodness-of-fit test based of strongly consistent simultaneous estimator for λ(·) and β derived in parer of Kukush and Chernova (2017) [6]. The test statistic is asymptotically chi-squared under null hypothesis. The power of the test under local alternatives is evaluated.

Keywords: Consistent estimator, goodness-of-fit test, local alternatives, Cox proportional hazards model, power of test, simultaneous estimator of baseline hazard rate and regression parameter.

Bibliography:
1. T. Augustin, An exact corrected log-likelihood function for Cox's proportional hazards model under measurement error and some extensions , Scand. J. Stat., 31 (2004), no. 1, 43-50.
2. H. Cartan, Differential Calculus , Hermann/Houghton Mifflin Co., Paris/Boston, MA, 1971. (Translated from French)
3. O. Chernova, A. Kukush, Confidence regions in Cox proportional hazards model with measurement errors and unbounded parameter set, Mod. Stoch. Theory Appl., 5 (2018), no. 1, 37-52.
4. C. Chimisov and A. Kukush, Asymptotic normality of corrected estimator in Cox proportional hazards model with measurement error, Mod. Stoch. Theory Appl., 1 (2014), no. 1, 13-32.
5. A. Kukush, S. Baran, I. Fazekas, and E. Usoltseva, Simultaneous estimation of baseline hazard rate and regression parameters in Cox proportional hazards model with measurement error, J. Statist. Res., 45 (2011), no. 2, 77-94.
6. A. G. Kukush, O. O. Chernova, Consistent estimation in Cox proportional hazards model with measurement errors and unbounded parameter set, Theor. Probability and Math. Statist., 96 (2017), 100-109.